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"Mixte" takes place in an all-male high school when girls are allowed in for the first time. Set in 1960s France, the series looks at the relationships and "hormonal fireworks" of the time. It will cover topics such as love, emancipation, sexuality and self-acceptance。现在是2147年，由于一种病毒的影响，男性变得不育，人类几乎濒临灭绝。生物学家塔尼娅正试图通过自我受精来阻止这一危机，她得到了名为VIDA的人工智能系统的帮助（帕兹·维嘉配音）。事情在阿扎里亚斯的突然出现后发生了变化，他是最后的男性之一，也是一个有着黑暗过去的旅行者。。